91亚色

Skip to main content Skip to local navigation

Paper of the month (September 2020) from Drs. Haas and Roudier research group

Nwadozi, E,听Rudnicki, M,听De Ciantis, M, et al.听High鈥恌at diet pre鈥恈onditioning improves microvascular remodelling during regeneration of ischaemic mouse skeletal muscle.听Acta Physiol.听2020;听229:e13449.听

Significance of the research:

Peripheral artery disease severely reduces blood flow to leg muscles, resulting in extensive and prolonged ischemic muscle damage. A multi-disciplinary team of scientists from 91亚色, University of Western Ontario and Karolinska Institute (Sweden) discovered that short-term administration of a high fat diet improves blood flow recovery, oxygen delivery and muscle health following ischemic damage. These findings demonstrate that dietary interventions may provide a tool to improve muscle recovery, functional independence and overall quality of life for individuals affected by severe muscle damage.