Canada Foundation for Innovation Archives | Research & Innovation /research/tag/canada-foundation-for-innovation/ Wed, 29 Jan 2025 19:53:22 +0000 en-CA hourly 1 https://wordpress.org/?v=6.9.4 CFI awards 91亚色 researchers more than $592,000 in research infrastructure /research/2012/10/17/cfi-awards-york-researchers-more-than-592000-in-research-infrastructure-2/ Wed, 17 Oct 2012 08:00:00 +0000 /researchdev/2012/10/17/cfi-awards-york-researchers-more-than-592000-in-research-infrastructure-2/ The Canada Foundation for Innovation (CFI) has awarded 91亚色 $592,631 in infrastructure funding to support the research of four 91亚色 professors. Ali Kazimi,听professor in Department of Film in the Faculty of Fine Arts,听will receive $143,186 in funding for industry standard infrastructure of a Stereoscopic 3D Lab @ 91亚色. The funding will听allow Kazimi to augment […]

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The (CFI) has awarded 91亚色 $592,631 in infrastructure funding to support the research of four 91亚色 professors.

Ali Kazimi,听professor in Department of Film in the Faculty of Fine Arts,听will receive $143,186 in funding for industry standard infrastructure of a Stereoscopic 3D Lab @ 91亚色. The funding will听allow Kazimi to augment and build upon the core of the stereoscopic research based production and post-production facility that has emerged out of the 3D FLIC (Film Innovation Consortium) project. S3DL @ 91亚色 will become the first dedicated facility of its type in Canada, enabling the study of stereoscopic 3D story-telling practices, their production and distribution, combined with insights and best practices gleaned from stringent psycho-physical tests and experimentation. S3DL will meld art and science in the best tradition of inter-disciplinary research, enabling one to push the boundaries of the knowledge generated by the other and vice versa in a deliberate, complementary and interactive way. Kazimi will work with researchers Laurie Wilcox and Rob Allison from 91亚色鈥檚 Centre for Vision Research on this project.

, professor in the听Department of Earth听& Space Science and Engineering, in the Faculty of听Science & Engineering,听will receive $135,671 in funding for the creation of a new laboratory to support the development of next-generation space technology. This new听technology听will be used to measure the composition of the atmosphere from space.听 The development of this advanced technology for atmospheric remote sounding will enhance Canada鈥檚 contribution to the global monitoring capacity for the climate and atmospheric communities. These contributions are necessary for Canada to maintain its access to global data sets and to provide input for the analysis and modeling of climate change and air quality 鈥 critical knowledge for a sustainable future.

, professor in the Department of Biology in the听Faculty of Science听& Engineering, will receive $158,237 in funding to establish a world-class laboratory to study local and large-scale brain circuits that underlie 鈥渁ttentional control鈥 of behavior 鈥 processes that determine what individuals attend to and how efficient individuals are in concentrating on the most relevant sensory information in our environment. Womelsdorf鈥檚 research examines how alterations in these brain circuits lead to dysfunctions of attentional control in major neuro-psychiatric disorders (including major depression, schizophrenia, and addiction). 听His research focuses on the key cognitive functions and on areas of the brain that underlie severe dysfunctions of attentional control in order to help improve diagnostic and therapeutic interventions.

Muhammed Yousaf, professor in the Department of Chemistry in the Faculty of Science and Engineering, will receive $155,537 in funding to develop infrastructure and state-of-the-art methodologies to cultivate new surface chemistries, tailor materials for fundamental studies of cell behaviour and develop next-generation biomolecular microarrays.听The funds will establish a new advanced biomolecular materials laboratory at 91亚色 to study how man-made materials interact with biological systems. The generation of these smart and responsive materials will provide a platform for new diagnostic screening assays of human disease and for studies of stem cell differentiation towards regenerative medical applications.

鈥淚 am delighted that the Canada Foundation for Innovation has recognized four of 91亚色鈥檚 leading researchers through these awards,鈥 said Robert Hach茅, 91亚色鈥檚 vice-president research & innovation.听 鈥淐FI鈥檚 investment in state-of-the-art infrastructure further enhances 91亚色鈥檚 vibrant research culture and enables our researchers to continue to build on and expand their innovative research programs.鈥

91亚色鈥檚 projects were part of a in CFI鈥檚 Leaders Opportunity Fund, which provides Canadian researchers with the necessary tools to carry out a range of frontier research. The funding supports 210 research projects across the country.

Minister of State Gary Goodyear announced the funding on Tuesday.

鈥淥ur government recognizes that investing in science and technology leads to a stronger, more innovative economy,鈥 he said. 鈥淲e understand that Canada鈥檚 research enterprise is critical to economic growth and job creation.鈥

鈥淕iven the right infrastructure, this talented group of innovators will create solutions that benefit Canadians and Canadians communities,鈥 said Gilles Patry, president and CEO of the CFI.

A complete list of recipients is available on the website.

Republished courtesy of YFile鈥 91亚色鈥檚 daily e-bulletin.

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VPRI reports on the research impact of the 2012 Federal Budget /research/2012/04/18/vpri-reports-on-the-research-impact-of-the-2012-federal-budget-2/ Wed, 18 Apr 2012 08:00:00 +0000 /researchdev/2012/04/18/vpri-reports-on-the-research-impact-of-the-2012-federal-budget-2/ Robert Hach茅, vice-president research & innovation, has issued this commentary听providing more details on the impact of the 2012 federal budget on research funding agencies and what it means for the 91亚色 research community: Vice-presidents of research from across Canada converged in Ottawa on April 13 to meet with the presidents of the Social Sciences听& Humanities […]

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Robert Hach茅, vice-president research & innovation, has issued this commentary听providing more details on the impact of the 2012 federal budget on research funding agencies and what it means for the 91亚色 research community:

Vice-presidents of research from across Canada converged in Ottawa on April 13 to meet with the presidents of the Social Sciences听& Humanities Research Council (SSHRC), Natural Sciences听& Engineering Council (NSERC), Canadian Institutes of Health Research (CIHR) and the Canada Foundation for Innovation (CFI), regarding the impact of the 2012 budget on their funding programs.

While the complete details of the consequences of budget 2012 remain to be fully worked out, the overall tone of the message emphasized the efforts being made by Tri-Council to protect and promote fundamental research, to describe where the new investments in the budget will be rolled out, and to give a first look at where the mandated cuts in programming and operations will occur.

Initial discussion emphasized new investments being made and the expression of support for basic research in the budget language (if not directly in the dollars being distributed). Not only was the overall budget to Tri-Council preserved in a budget cycle where听five to听ten per cent听cuts in overall budgets were the norm, but new investments were committed to support a number of new and existing programs. Thus CANARIE, Genome Canada and the CFI all received major infusions of funding that were accompanied by focused investments (in mental health etc.). While there is no explicit new funding for basic research in this budget, the lack of an overall funding reduction place Tri-Council in rare company around the federal budget table this year.

Over the last number of years, Tri-Council agencies were asked to undertake a strategic review of their expenditures, a process which required a review of all program spending and assessment of savings. The review process identified areas where savings could be achieved in order to redirect funding within the organization for new initiatives or to other government priorities.

While these are clearly no longer the heady times of the early 2000s, when Tri-Council budgets grew rapidly in a largely unrestricted manner, overall support for university-led research by the federal government remains comparatively strong and researchers should be encouraged by this. However, it is clear that at all levels, the funders of university research continue to move towards an emphasis on how the results of university-led research translates into tangible benefits for Canadian society and the Canadian economy. Here it is important for researchers to continue their efforts to explain and educate government and other funders on the need to support fundamental research as the bedrock on which university-led research is built.

It is also crucial to emphasize the need for programing that provides funding for making connections amongst researchers and sustaining the basic infrastructure needed for individual research programs.听We can all, in following up on the steps presently been taken by Tri-Council, encourage the continued protection and development of core people and basic research programing within Tri-Council, and emphasize at every opportunity that the development of Canada鈥檚 Innovation Agenda can only be successful if done in partnership with development of our discovery agenda.

For the full commentary, which includes specific details of anticipated programming changes, please click here.

Republished courtesy of YFile鈥 91亚色鈥檚 daily e-bulletin.

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VPRI responds to the federal budget /research/2012/04/12/vpri-responds-to-the-federal-budget-2/ Thu, 12 Apr 2012 08:00:00 +0000 /researchdev/2012/04/12/vpri-responds-to-the-federal-budget-2/ Robert Hach茅, vice-president research & innovation, has issued this commentary听on the federal budget to the 91亚色听community. The recent federal budget reinforced the importance the government is placing on putting its fiscal house in order with some programs receiving cuts in excess of 10 per cent. Within that overall context of restraint is a听welcome affirmation of […]

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Robert Hach茅, vice-president research & innovation, has issued this commentary听on the federal budget to the 91亚色听community.

The recent federal budget reinforced the importance the government is placing on putting its fiscal house in order with some programs receiving cuts in excess of 10 per cent.

Within that overall context of restraint is a听welcome affirmation of the government鈥檚 strong commitment to research and innovation, with funding programs largely preserved and substantial new commitments听made.听 At the same time, the new investments focus predominantly on Canada鈥檚 innovation agenda, while the importance of supporting fundamental research is acknowledged in less tangible ways. It is explicitly stated on page 271 of the budget document that "programming in support of basic research, student scholarships and industry-related research initiatives and collaborations are preserved."

The budget has reaffirmed the importance of Tri-Council funding by returning mandated budget cuts in the form of $37 million in new investment, albeit with a focus on industry-academic partnerships.听This leaves Tri-Council with stable overall budget envelopes in the present fiscal year and the hope that next year鈥檚 mandated budget cut of $31.3 million may be similarly rescued through the infusion of additional new monies.

The long-term investment in the Canada Foundation for Innovation ($500 million over five years, beginning in 2014) and the doubling of support for graduate students to gain workplace experience through the Industrial Research听& Development Internship Program, are further positive signals of the importance the government places on high-quality university research, and in attracting and retaining top students and researchers.

Other notable investments in research and higher education include:

  • $40 million over two years to support Canada鈥檚 Advanced Research & Innovation Network鈥檚 (CANARIE) operation of Canada鈥檚 ultra-high-speed research network;
  • $60 million for Genome Canada to launch a new applied research competition in the area of human health, and to sustain the Science and Technology Centres until 2014-2015;
  • $10 million over two years to the Canadian Institute for Advanced Research to link Canadians to global research networks;
  • $5.2 million in 2012鈥2013 to establish and integrate a network of mental health-related researchers in听the Canadian Depression Research听& Intervention Network;
  • $67 million to assist the National Research Council (NRC) refocus on business-led, industry-relevant research, as well as doubling the contribution budget of the NRC鈥檚 highly successful cross-Canada Industrial Research Assistance Program (IRAP) in aid of small and medium enterprises.

These investments can only be seen as encouraging and a reflection of continuing strong support for university sector research. They provide important building blocks to developing knowledge, creativity and innovation within universities, now and into the future.听 This is a reality the government recognizes. We are fortunate to have experienced a significant upswing in university research investments over the last decade, with investments having nearly quadrupled since the mid-1990s and continuing to rise despite economic setbacks.听Budget 2012 presents a stable agenda for research funding听鈥 delivering a longer term message on research and innovation that reinforces the government鈥檚 goal, 鈥渢o position Canada for increased success in the global economy that depends more and more on knowledge and innovation as a key driver of long-term competitiveness.鈥

Canada鈥檚 societal well-being and future economic health depend greatly on our capacity to innovate and build a highly competitive advantage.听 This is a vision that 91亚色 shares and will continue to foster in benefiting our researchers.听With the sustained support towards higher education and excellence in research and technology, we will continue to work with the government to ensure the continuation of these vital investments 鈥 and to reinforce the need to invest equally in the ongoing development of fundamental research.

Republished courtesy of YFile鈥 91亚色鈥檚 daily e-bulletin.

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Study finds people can see the forest without the trees /research/2011/12/19/study-finds-people-can-see-the-forest-without-the-trees-2/ Mon, 19 Dec 2011 10:00:00 +0000 /researchdev/2011/12/19/study-finds-people-can-see-the-forest-without-the-trees-2/ When you look at someone鈥檚 office, what do you see 鈥 the desk, some pens, a computer? Do you know it鈥檚 an office because of the objects in it, or by taking in the entire scene? What 91亚色 psychology Professor Jennifer Steeves and PhD candidate Caitlin Mullin (MA 鈥08) have found is that it鈥檚 not […]

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When you look at someone鈥檚 office, what do you see 鈥 the desk, some pens, a computer? Do you know it鈥檚 an office because of the objects in it, or by taking in the entire scene? What 91亚色 psychology Professor Jennifer Steeves and PhD candidate Caitlin Mullin (MA 鈥08) have found is that it鈥檚 not necessary to recognize the objects to identify the scene, in this case an office.

鈥淵our ability to recognize objects and your ability to recognize scenes are independent,鈥 says Steeves.听

Their study is published in the December issue of the Journal of Cognitive Neuroscience 鈥 鈥淭MS to the Lateral Occipital Cortex Disrupts Object Processing but Facilitates Scene Processing鈥.

Left: Psychology Professor Jennifer Steeves applies rTMS stimulation to听PhD candidate Caitlin Mullin. Images of Mullin's brain can be seen on the adjacent screen

The finding discounts an earlier theory that scene perception relies on the recognition of individual objects and instead finds that the gist of a scene can be ascertained by its spatial layout alone.

Steeves and Mullin conducted two experiments. Both showed that when the ability to see objects is impaired, the brain can still determine what it鈥檚 looking at by taking in the scene. But what surprised the researchers is that when object recognition was temporarily knocked out, the ability to categorize scenes, such as distinguishing a forest from a cityscape, increased.

鈥淚t鈥檚 like you can see the forest better when you can鈥檛 see the trees,鈥 says Steeves, who heads up the Perceptual Neuroscience Lab听in 91亚色's . 鈥淲e didn鈥檛 expect this at all. The stimulation听must be releasing some inhibitory process in people's brains.鈥

The experiments involved nine individuals with healthy brains. Repetitive transcranial magnetic stimulation (rTMS) was applied to the left lateral occipital cortex (LO), the object processing area of the brain just behind each ear, to disrupt object processing. This was done while showing the subjects pictures of scenes and objects.

Right: Jennifer Steeves

The idea was to see how the LO contributed to the perception of scenes. The rTMS momentarily scrambled the neurons in the LO, preventing the subject from recognizing the objects, but they were able to categorize the scenes more quickly and accurately than before. The first experiment involved using a longer disruption time for object processing than that used in the second experiment.

鈥淭here was a split second interruption to the brain in the second experiment,鈥 says Steeves. Still, the second experiment confirmed the findings of the first. 鈥淚t鈥檚 a really robust effect. The TMS showed us that even though the two functions are independent, they still work together.鈥

Steeves and Mullin are now doing research find out what other parts of the brain are affected when rTMS is applied to specific areas. 鈥淲e鈥檙e finding so far that stimulating one region can have an effect on other areas,鈥 says Mullin.

The research is part of the nuts and bolts of mapping the brain, which could have implications down the road in helping people with brain injuries or informing computer modelling. 鈥淲hat鈥檚 nice is we鈥檙e learning about networks in the brain,鈥 says Steeves. And that is where it all starts.

The experiments were funded through grants from the Canada Foundation for Innovation, the Ontario Research Fund and the Natural Sciences & Engineering Research Council of Canada.

By Sandra McLean, YFile writer

Republished courtesy of YFile鈥 91亚色鈥檚 daily e-bulletin.

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91亚色 psychologist studies the 'spacing effect' in teaching /research/2011/02/08/york-psychologist-studies-the-spacing-effect-in-teaching-2/ Tue, 08 Feb 2011 10:00:00 +0000 /researchdev/2011/02/08/york-psychologist-studies-the-spacing-effect-in-teaching-2/ In the late 1800s, German psychologist Hermann Ebbinghaus set out to memorize hundreds of nonsense syllables and discovered it was more efficient to space out his study sessions than to try to learn long lists in one sitting [wrote The Globe and Mail Feb. 7]: Hundreds of studies carried out since have established the power […]

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In the late 1800s, German psychologist Hermann Ebbinghaus set out to memorize hundreds of nonsense syllables and discovered it was more efficient to space out his study sessions than to try to learn long lists in one sitting [wrote ]:

Hundreds of studies carried out since have established the power of what is now known as the 鈥渟pacing effect鈥澨 how people can better remember faces, words and historical facts if they spread out their study time rather than attempting one long cram session.

But most of the experiments have involved adults, said 91亚色 psychologist Nicholas Cepeda [Faculty of Health], who has begun to study the spacing effect in Ontario classrooms. He wants to come up with simple recommendations that will help teachers capitalize on the effect to improve how much students learn and retain.

Cepeda's studies include: What kind of spacing is most effective? Should lessons and subsequent review sessions be a week apart? Or is a gap of several months better? Are cumulative tests an effective teaching tool because they cover material taught earlier in the year as well as the most recent lessons?

Cepeda is probing deeper questions as well. What is it about the brain that makes the spacing effect so powerful? What can it tell us about how memory works? Cepeda was recently awarded a $100,777 grant from the Canadian Foundation for Innovation to buy equipment that will allow him to measure the electrical activity in the brains of children when they learn something for the first time, compared to when they study it again several months later.

He expects that re-learning material a second or third time is the result of different, more intense brain activity. 鈥淚f you have forgotten the material, the brain may think it has to pay more attention.鈥

Cepeda also wants to assess the value of cumulative tests, which include questions on material students learned earlier in the year and could be a valuable teaching tool.

He said it is frustrating how little research is done to translate the discoveries psychologists and neuroscientists make about memory and learning into effective teaching strategies. In the United States, the Institute of Education Sciences funds this kind of research, but there is no equivalent agency in Canada, said Cepeda, who has applied to the US institute to do more studies in Toronto classrooms.

鈥淎s psychologists, we are sometimes scared to tell teachers what to do because we may end up telling them to do something that works in the lab that doesn鈥檛 work in the real world. We really do need to be testing these things in the classroom.鈥

Republished courtesy of YFile鈥 91亚色鈥檚 daily e-bulletin

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CFI awards 91亚色 researchers $274,000 in funding /research/2011/01/26/cfi-awards-york-researchers-274000-in-funding-2/ Wed, 26 Jan 2011 10:00:00 +0000 /researchdev/2011/01/26/cfi-awards-york-researchers-274000-in-funding-2/ Funding will support three projects in biology, kinesiology and psychology The Canada Foundation for Innovation (CFI) has awarded 91亚色 $274,689 in infrastructure funding to support the research of three 91亚色 professors. Olivier Birot,听professor in the School of Kinesiology & Health Science in 91亚色's Faculty of Health and a member of the Muscle Health Research […]

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Funding will support three projects in biology, kinesiology and psychology

The Canada Foundation for Innovation (CFI) has awarded 91亚色 $274,689 in infrastructure funding to support the research of three 91亚色 professors.

,听professor in the School of Kinesiology & Health Science in 91亚色's Faculty of Health and a member of the Muscle Health Research Centre, will receive $79,260 to support his research on muscle microcirculation in health and diseases. Birot鈥檚 research examines how peripheral vascular disease (PVD) affects key molecular mechanisms that regulate the formation of blood vessels in muscles. PVD is characterized by insufficient blood supply in leg muscles, leading to suffering, reduced mob ility and eventually amputation. 听PVD affects more than one million Canadians and is a frequent complication for patients with obesity, Type 2 diabetes or chronic heart failure.

Right: Olivier Birot

Nicholas Cepeda, professor in the Department of Psychology in the Faculty of Health, will receive $100,777 to establish a developmental cognitive neuroscience laboratory for research on learning and memory, cognitive flexibility and musical training. His research has shown a 300 per cent improvement in students鈥 long-term recall of factual information, merely by changing the timing of when a particular curriculum item is taught and re-taught 鈭 with no increase in teaching time. The project鈥檚 musical training research will provide information about the brain functions of musicians and non-musicians, including processing speed, working memory, inhibition, attentional control and task-switching skills.

Left: Nicholas Cepeda

,听professor and a Canadian Institutes听of Health Research New Investigator in the听Department of Biology in听91亚色's , will receive $94,652 to support multi-faceted research in integrative neuroendocrinology and physiology. His research on the neuroendocrine regulation of growth, reproduction and body weight in fish could help aquaculture industry to improve the feeding, growth and reproduction of cultured fish. The funding also provides critical equipment for cutting-edge research on the neuroendocrine defects underlying diabetes and obesity, and may help to develop innovative pharmacological and cell-based therapies to help Canadians and others in their fight against these metabolic diseases.

Left: Suraj Unniappan

鈥淭hese projects demonstrate 91亚色鈥檚 excellence in health and science research,鈥 said Stan Shapson, vice-president research & innovation. 鈥淭he questions Professor Birot's and Cepeda's projects explore concerning muscle health and learning and cognition reflect the relevance and disciplinary strengths of our psychology and kinesiology researchers, while Professor Unniappan's project illustrates the industrial applications that may flow from support for basic research. We fully support the importance of the CFI鈥檚 investments in state-of-the-art infrastructure and the world-class research they enable at 91亚色.鈥

91亚色鈥檚 projects were part of a in 's Leaders Opportunity Fund, which provides Canadian researchers with the necessary tools to carry out a range of frontier research. The funding supports 339 leading researchers and 245 projects at 48 Canadian research institutions.

Gary Goodyear, minister of state (science听& technology), made the announcement in Ottawa, Ontario on Jan.听21. 鈥淪upporting science is key to Canada鈥檚 future economic growth,鈥 said Goodyear. 鈥淥ur government's commitment to helping universities attract and retain world-leading research talent will lead to discoveries that improve Canadians' quality of life and create new jobs."

鈥淎ccess to modern, cutting-edge equipment and facilities is imperative in the 21st century," said Gilles听Patry, president听& CEO of the CFI. 鈥淔or more than a decade, the CFI has provided thousands of world-class researchers with the tools they need to do their work. Without the right infrastructure, they simply wouldn't be in Canada.鈥

A complete list of CFI recipients is available on the website.

By Elizabeth Monier-Williams, research communications officer, with files courtesy of Janice Walls and Melissa Hughes

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Professor Michael Jenkin's AQUA robot gets four flippers and a clever brain /research/2010/12/08/professor-michael-jenkins-aqua-robot-gets-four-flippers-and-a-clever-brain-2/ Wed, 08 Dec 2010 10:00:00 +0000 /researchdev/2010/12/08/professor-michael-jenkins-aqua-robot-gets-four-flippers-and-a-clever-brain-2/ A team of researchers from 91亚色 has helped created a robot with the smarts to think for itself as it swims underwater, wrote Metro (Canada) Dec. 7: The team, led by Michael Jenkin, a computer science professor in 91亚色鈥檚 Faculty of Science & Engineering, is working together with teams from McGill University and Dalhousie […]

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A team of researchers from 91亚色 has helped created a robot with the smarts to think for itself as it swims underwater, wrote (Canada) Dec. 7:

The team, led by , a computer science professor in 91亚色鈥檚 Faculty of Science & Engineering, is working together with teams from McGill University and Dalhousie University to build the highly advanced AQUA robot, which resembles an otter and uses flippers to propel itself around underwater. Despite its cute, toy-like appearance, AQUA is intelligent enough to understand visual commands and perform complex under water manoeuvres.

Jenkin's team recently created an underwater control tablet that lets an operator interact with AQUA directly and much more quickly 鈥 a crucial feature when investigating dangerous, unknown environments like shipwrecks. 鈥淲e want to make vehicles that are more intelligent, that understand their world better and can interact with the world better. The underlying goal is to enhance our understanding of how to build intelligent, autonomous systems,鈥 Jenkin said.

Jenkin, a member of the , is one of the researchers based in 91亚色鈥檚 new state-of-the-art Sherman Health Science Research Centre, which officially opened on Sept. 14. He leads the Canadian Centre for Field Robotics laboratory, which is based on the building鈥檚 main level.

The centre is supported by a grant from the . The AQUA project is funded in part by the .

Posted by Elizabeth Monier-Williams, with files courtesy of YFile鈥 91亚色鈥檚 daily e-bulletin

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Video: Professor Laurence Packer on why and how to make your garden bee-friendly /research/2010/09/22/video-professor-laurence-packer-on-why-and-how-to-make-your-garden-bee-friendly-2/ Wed, 22 Sep 2010 08:00:00 +0000 /researchdev/2010/09/22/video-professor-laurence-packer-on-why-and-how-to-make-your-garden-bee-friendly-2/ Without bees, we wouldn鈥檛 have coffee to drink at breakfast, tomatoes in your sandwich at lunch or fruit for a snack on the go. While bee populations all over the world are in trouble, there are lots of things individuals can do to create bee-friendly gardens 鈥 even if your personal green space is limited […]

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Without bees, we wouldn鈥檛 have coffee to drink at breakfast, tomatoes in your sandwich at lunch or fruit for a snack on the go. While bee populations all over the world are in trouble, there are lots of things individuals can do to create bee-friendly gardens 鈥 even if your personal green space is limited to a condo balcony.

Here's Professor Laurence Packer from 91亚色鈥檚 Department of Biology in the on what you can do to help the world鈥檚 bees in your backyard:

Packer travels the world tracking many of the 19,500 described species of wild bees. While his perspective is international, Packer鈥檚 backyard is a great example of a bee-friendly space and is featured in the video. He is also the author of . All proceeds form his book will be directed toward bee conservation research.

In 2010, Packer was featured on CBC鈥檚 The Nature of Things, hosted by David Suzuki. The episode, 鈥溾, highlights dramatic declines in North America鈥檚 wild bee and honey bee populations, and explores what the disappearance and decline of these insects tells us about larger ecological problems. The episode is also available for download on. Packer鈥檚 segment runs from the 3:30 mark through to 6:30.

PhD student Jason Gibbs, who works in Packer鈥檚 laboratory and has collaborated with him on research publications, also recently made national news headlines by documenting 19 new bee species, one of which he discovered during his commute from downtown Toronto to 91亚色.

To read more about their work, visit Packer鈥檚 Website or search for past stories in the Research News archive using the and tags.

Packer's research is funded by the (NSERC) and the (CFI).

By Elizabeth Monier-Williams, research communications officer.

Video production by Elizabeth Monier-Williams, research communications officer, Elizabeth Teodorini, alumni communications manager, and Robert Denault and Perry Walker in the Learning Technology Services unit.

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Professor Dorota Crawford's research shows misoprostol prevents cell communication /research/2010/07/09/professor-dorota-crawfords-research-shows-misoprostol-prevents-cell-communication-2/ Fri, 09 Jul 2010 08:00:00 +0000 /researchdev/2010/07/09/professor-dorota-crawfords-research-shows-misoprostol-prevents-cell-communication-2/ Drug has been linked to neurodevelopmental defects associated with autism A 91亚色 study has shown for the first time how the drug misoprostol, which has been linked to neurodevelopmental defects associated with autism, interferes with neuronal cell function. It is an important finding because misoprostol is similar in structure to naturally occurring prostaglandins, which […]

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Drug has been linked to neurodevelopmental defects associated with autism

A 91亚色 study has shown for the first time how the drug misoprostol, which has been linked to neurodevelopmental defects associated with autism, interferes with neuronal cell function.

It is an important finding because is similar in structure to naturally occurring prostaglandins, which are the key signalling molecules produced by fatty acids in the brain.听The drug is听used to prevent ulcers in people who take certain arthritis or pain medicines, including aspirin, that can cause ulcers. It protects the stomach lining and decreases stomach acid secretion.

Past clinical studies have shown an association between misoprostol and severe neurodevelopmental defects including autism symptoms. Those studies looked at cases in Brazil in which women misused the drug early in pregnancy in unsuccessful attempts to terminate their pregnancies.

The 91亚色 study examined mouse neuronal cells to discover how the drug actually interferes at a molecular level with prostaglandins, which are important for development and communication of cells in the brain.

鈥淓arly in the first trimester of pregnancy, neuronal cells reach out to communicate with one another,鈥 says Dorota Crawford, a professor in the School of Kinesiology & Health Science in 91亚色鈥檚 Faculty of Health.听鈥淥ur study shows that misoprostol interferes with this process by increasing the level of calcium ions in neuronal extensions, which reduces the number and length of these extensions. It prevents the cells from communicating with each other. If changes in prostaglandin level alter the development or differentiation of cells, it may have a physiological impact.鈥

Left: Dorota Crawford

Crawford and Javaneh Tamiji, who undertook the research for her master鈥檚 thesis in the Neuroscience Graduate Diploma Program at 91亚色, co-authored a study published online in the journal Biochemical and Biophysical Research Communications: 鈥淧rostaglandin E2 and misoprostol induce neurite retraction in Neuro-2a cells鈥.

There is no indication that women in Canada are misusing misoprostol to terminate pregnancies, and in fact the drug is used safely for other purposes such as treatment and prevention of gastrointestinal ulcers. However, during early neuronal development the drug misoprostol or other environmental factors such as infections or inflammations, which can also increase the level of prostaglandins, may interfere with normal brain function, says Crawford.

Right: Javaneh Tamiji

Crawford and Tamiji focused on the drug misoprostol because they had evidence from听clinical studies of the neurotoxic effects of the drug. They used misoprostol and the naturally occurring prostaglandins side by side in their study and found that both compounds produced the same effects on neuronal cell function.

The study shows that misoprostol interferes with the prostaglandin pathway in a dose-dependent manner 鈥 in other words, the higher the dose, the greater the problems created.

鈥淲hat that indicates to us is whether it is infection that will activate it or whether it is the drug, it will cause the same effect,鈥 says Crawford.

Now that it has been shown that misoprostol affects interaction between cells, the next step will be to do animal studies on mice to examine the physiological impacts on particular parts of the brain, she says.

Crawford鈥檚 lab is one of very few in the world that has adopted a multidisciplinary approach to the study of autism spectrum disorders, using molecular techniques to understand the link between causative biological factors (genes and environment) and the behavioural expression.

This research was funded by the . The provided equipment used in the study.

It has also received coverage on MedicalNewsToday.com:

A 91亚色 study has shown for the first time how the drug misoprostol, which has been linked to neurodevelopmental defects associated with autism, interferes with neuronal cell function.

91亚色 Professor Dorota Crawford, of the School of Kinesiology & Health Science in the Faculty of Science & Enginering, and graduate student Javaneh Tamiji, who undertook the research for her master鈥檚 thesis in the Neuroscience Graduate Diploma Program at 91亚色, co-authored a study published online in the journal Biochemical and Biophysical Research Communications: 鈥淧rostaglandin E2 and misoprostol induce neurite retraction in Neuro-2a cells鈥.

By Janice Walls, media relations officer

Republished courtesy of YFile鈥 91亚色鈥檚 daily e-bulletin.

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91亚色 hosts its first Neuroscience Research Day /research/2010/06/21/york-hosts-its-first-neuroscience-research-day-2/ Mon, 21 Jun 2010 08:00:00 +0000 /researchdev/2010/06/21/york-hosts-its-first-neuroscience-research-day-2/ The first cohort of students graduating from 91亚色鈥檚 Neuroscience Graduate听Diploma Program will present their leading-edge research today as part of the University鈥檚 first Neuroscience Research Day. The presentations will take place from 9am to 3:30pm in 163 Behavioural Sciences Building on 91亚色's Keele campus. Fifteen students will offer summaries of their research. The students come […]

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The first cohort of students graduating from 91亚色鈥檚 Neuroscience Graduate听Diploma Program will present their leading-edge research today as part of the University鈥檚 first Neuroscience Research Day. The presentations will take place from 9am to 3:30pm in 163 Behavioural Sciences Building on 91亚色's Keele campus.

Fifteen students will offer summaries of their research. The students come to the program from different backgrounds, including听computer science, psychology, biology, and kinesiology听& health science.

"This day marks the culmination of two years of intense neuroscience studies for our first group of students," says Professor Doug Crawford (left), and the program鈥檚 coordinator. "They are a wonderful group and I am extremely proud of them"

Today鈥檚 presentations cover a wide range of approaches to neuroscience, ranging听from research on molecular and cellular mechanisms in nerve cells and the relationship between the elements of neural systems, to the study of behaviour of whole organisms.

Psychology Professors Shayna Rosenbaum and Kari Hoffman have been hard at work coordinating the听Neuroscience Research Day. 鈥淲e began a neuroscience graduate diploma program at 91亚色 in 2008. It combines the interests of the psychology, biology, and kinesiology听& health sciences program,鈥 says Rosenbaum. 鈥淭his is the end of the second year of the program, which is a two-year consecutive program that is done in conjunction with the graduate students鈥 home department and their degree. [They are given a diploma in addition to their degree.] While the Neuroscience Research Day program is focused on the students, the event is also听a celebration of the wide range of research interests among our neuroscience research faculty.鈥

Above: The class of 2010 and neuroscience faculty

The graduating students听will be听presenting a range of projects, says Rosenbaum, that draw听on different methodologies.听Some students will be showcasing work done using a听molecular approach, while others听will be presenting research that looks at听neuroscience from a systems focus. Other students, says Rosenbaum, have relied on neuroimaging methods and some have done their research with patient populations.听The breadth of projects that will be presented during the research day, says Rosenbaum, mirrors the program faculty's听multidisciplinary approach to neuroscience.

Left: Shayna Rosenbaum

The following is a snapshot of some of the 15 research projects that will be presented today:

David Cappadocia (BSc Spec. Hons. 鈥08), is a second-year master's student听working with Crawford. Cappadocia听will present on听his research into听how the brain remembers different features of an object, so that when it is time to act on the object, it can be discriminated from other similar objects.

Caitlin Mullin (MSc 鈥08), a PhD student, is studying how different parts of the brain form representations of the visual world around us. Mullin is听using transcranial magnetic stimulation to apply a brief magnetic pulse to a specific part of the brain. This temporarily deactivates the brain region, allowing Mullin to determine how it functions. Mullin听is supervised by 91亚色 psychology Professor Jennifer Steeves.

PhD student Krista Kelly will present her research that looks into the effects of losing one eye early in life. Specifically, Kelly is researching how that loss affects brain organization and听visual ability. Working under the supervision of Steeves, Kelly is using听functional brain imaging to correlate findings with听behavioural measures of performance.

Master's students Javaneh Tamiji (BSc Spec. Hons. 鈥08) and Shannon Lozinsky are working with听kinesiology Professor Dorota Crawford. They听will present their research on the听causes of autism, a disorder of the brain. Using state-of-the-art equipment funded by the , Tamiji and Lozinsky听are investigating how听environmental agents, such as drugs taken during early pregnancy, affect function and communication of cells in the brain. The goal of their project is to听achieve a听better understanding of听what is different or missing in the brains of individuals with autism.

91亚色 PhD student Debi Stransky (BSc Spec. Hons. 鈥06, MSc 鈥08) is investigating stereoscopic听depth perception across a large range of depth offsets under the supervision of 91亚色 psychology Professor Laurie Wilcox. There is convincing evidence that there is a separate depth processing mechanism for images that cannot be fused into a single percept.听Stransky is determining the quality of depth perceived from such stimuli and if these percepts are subserved from distinct neural mechanisms. Her work is funded听by a postgraduate fellowship from the Natural Sciences & Engineering Research Council of Canada (NSERC).

91亚色 PhD student Inna Tsirlin (BSc Spec. Hons. 鈥04, MSc 鈥06) is studying听depth perceptions from monocular occlusions. These are regions in a scene that are visible to one eye, but not to the other because they are occluded, for instance by objects in the foreground. For many years this information was considered noise. Tsirlin's work has shown that monocular occlusions help define the boundaries between objects and backgrounds, and can even provide quantitative depth information. Tsirlin is working听under the supervision of Wilcox and her work is funded by a postgraduate fellowship from NSERC.

Left: Kari Hoffman

PhD student Stephanie Hornyak, who specializes in clinical neuropsychology, is investigating how brain regions communicate with each other to support spatial memory of well-known environments learned long ago. Under the supervision of 91亚色 psychology Professor Shayna Rosenbaum, she has used an innovative method of combining functional MRI with multivariate statistics, which will help predict how brain networks may break down in patients who suffer from spatial disorientation.

91亚色 master鈥檚 student Adrian Bartlett (BA Spec. Hons. 鈥08) is studying how the eye movements we use to scan the environment may shape the neural basis of object recognition. Using spectral analysis of neuronal population activity, his research has revealed that eye movements help coordinate the activity of neurons, leading to a stronger, more efficient code of what we鈥檙e viewing, Bartlett is the recipient of an NSERC Canada Graduate Scholarship and is supervised by psychology Professor Kari Hoffman.

鈥淎ll the research being presented is very exciting and it is also an important听year because 91亚色 has acquired functional magnetic resonance imaging (fMRI) technology,鈥 says Rosenbaum.听鈥淭he day听also听offers students another forum for networking and will help them build future collaborations.鈥

Everyone in the University community is invited to attend the presentations. The deans of the , and Graduate Studies will also give presentations.

For more information, visit the Neuroscience Graduate Diploma Web site.

By Jenny Pitt-Clark, YFile editor

Republished courtesy of YFile鈥 91亚色鈥檚 daily e-bulletin.

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