The first annual Muscle Health Awareness Day, organized by 91亚色鈥檚聽 Muscle Health Research Centre, will bring together the latest findings on the contribution made by heart muscle and skeletal muscle to overall health and wellbeing.

A wide range of collaborative research on muscle biology research is being done at 91亚色鈥檚 Muscle Health Research Centre, by researchers from the Faculty of Health and the Faculty of Science and Engineering; scientists are examining muscle development, disease, metabolism, blood supply, injury and regeneration, as well as adaptation of muscle to exercise. Using molecular, cellular and whole-body techniques, a major goal is to learn how Canadians can benefit from exercise through adaptations in the metabolism and structure of muscle, says Professor David Hood, director of the Muscle Health Research Centre and Canada Research Chair in Cell Physiology.

Researchers from the Centre will be joined by scientists from the University of Toronto, Sick Kids Hospital, the University of Guelph, McMaster University and Brock University, who will present their findings during four sessions. More than 50 poster presentations will also be on display at Muscle Health Awareness Day, showing the wide variety of muscle research being done by graduate students.

The four sessions during Muscle Health Awareness Day include:

1. Metabolism 鈭� will provide a description of important protein and fat metabolism pathways in health and disease. Emphasis will be on how enzymes responsible for synthesizing new proteins in muscle cells are activated, and how fats are taken up into muscle cells and metabolized. This has important implications for muscle wasting conditions, as well as obesity.
2. The Cardiovascular System 鈭� will examine how heart muscle adapts to stress in various ways.聽 The session will focus on understanding how heart muscle cells respond to stressors such as exercise and heat and how novel methods can be used to identify important proteins that are found in cardiac disease conditions. It will also provide information about heart and smooth muscle signaling during hemodynamic stress, such as high blood pressure.
3. Muscle Development and Satellite Cells 鈭� will describe some of the important molecules that regulate the process by which large, mature muscle cells develop from small precursor cells that fuse together, allowing muscle contraction and providing the energy for contraction to take place. Research will also be presented about the importance of precursor cells (called satellite cells) in adult muscle, and how they respond to exercise and aging.
4. Exercise, Metabolism and Disease 鈭� will provide an understanding of important enzymes in the mitochondria that regulate carbohydrate and fat metabolism, and will relate mitochondrial function (the powerhouse of the cell) to states of physical activity and obesity in youth. Information will also be provided about muscle diseases that lead to exercise intolerance and muscle cramps.

WHEN: 聽聽聽聽聽聽聽聽聽聽聽 Friday May 28, 9am to 5 pm
WHERE: 聽聽聽聽聽聽聽聽聽 Computer Science & Engineering Lobby and Lecture Hall B, Keele campus
INFO: 聽聽聽聽聽聽聽聽聽聽聽聽聽 /mhrc/Musclehealthday.htm.
MAP:聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽 See # 19 on map, /yorkweb/maps/index.htm

By Janice Walls, media relations officer.

The post 91亚色 to host muscle and healthy living research forum Friday, May 28 appeared first on Research & Innovation.

Scientists at the new Centre for Research on Biomolecular Interactions (CRBI)聽at 91亚色, which officially opens today,聽aim to make discoveries that will impact global health care and the treatment of diseases.

Understanding the foundation of key interactions at the molecular level is the research focus at the聽new centre,聽which will be housed聽in聽91亚色's Faculty of Science聽& Engineering. Scientists will study how biomolecules interact at every level聽鈥� from pure molecules to single cells to the entire organism. They will examine these interactions聽under normal circumstances and in the development of a disease. Their research will result in a deeper understanding of the聽"mechanical" changes that occur in disease during biomedical interactions that have gone awry.

The CRBI members have already been busy at work聽exploring important molecular interactions of biomolecules such as nucleic acids (DNA and RNA) and proteins.聽With the formation of the centre, they will now聽have the opportunity to combine their forces and share resources. The centre encompasses聽faculty members and research teams that include聽more than聽70 graduate students, research associates, postdoctoral fellows and undergraduate students.聽 Researchers from chemistry and biology departments at 91亚色 include Professors Gerald Audette, Samuel Benchimol, Kathy Hudak, Philip Johnson, Sergey Krylov (director), John McDermott,聽Andrew White and Derek Wilson.

Above: Some of the members of the new Centre for Research on Biomolecular Interactions at 91亚色. Front row, from left:聽Sergey Krylov, John McDermott and聽Derek Wilson.聽Middle row, from left:聽Philip Johnson and聽Gerald Audette.聽Back row, from left:聽Mark Bayfield and聽Andrew White. Missing from the photo are Professors Samuel Benchimol and Kathy Hudak.

The group鈥檚 combined expertise, which varies聽from analytical and physical chemistry to structural, cell and molecular biology,聽provides an opportunity for聽research projects to be pursued in an interdisciplinary and comprehensive manner. The team uses cutting-edge approaches to gain full understanding of key molecular players and events that can lead to disease, and by doing so,聽hopes to address聽prevention and future treatment of many diseases.

The centre is bustling with energy and activities, and future plans include extending the centre鈥檚 external and industry collaborations, launching a new peer-reviewed journal, Journal of Biomolecular Interactions, and hosting a research retreat.

鈥淭he creation of the Centre for Research on Biomolecular Interactions is an important step that will strengthen the existing collaborations and foster new ones at 91亚色 and beyond,鈥� says 91亚色 chemistry Professor Sergey Krylov,聽director of the CRBI and Canada Research Chair in Bioanalytical Chemistry. 鈥淭he centre is a nucleus for great researchers and it encourages a stimulating and cooperative environment. We have energy, enthusiasm and research synergy; I anticipate our collaborative research will lead to advances in various areas including disease detection and understanding of disease processes.鈥�

There will be an opening celebration for the CRBI today in the Seymour Schulich Building on 91亚色's Keele campus. The invitation-only event includes聽a reception and a keynote lecture by Professor Jack Greenblatt from the Terrace Donnelly Centre for Cellular & Biomolecular Research at the University of Toronto,聽who will address the importance of studying biomolecular interactions in his talk titled 鈥淧rotein complexes and functional pathways in yeast, bacteria and mammalian cells鈥�.

From YFile - 91亚色's daily e-bulletin

The post New centre looks at biomedical interactions appeared first on Research & Innovation.